Everything To Know About Infection (UTI, Sepsis), Antimicrobial Resistance & Its Treatment

Aaliyah Jain

So, let’s talk about something we’d all rather avoid but need to know about: infections, like UTIs and sepsis. If you’re anything like me, you probably don’t spend a lot of time thinking about them—until you have to. But trust me, after diving into this topic, I realized just how important it is to be clued up. And guess what? There’s some groundbreaking tech out there that could literally save lives, including yours. Let me break it down for you.

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UTIs and Sepsis: The Real Deal

Let me start with UTIs, which are super common—for us women, especially when pregnant. If you’ve ever had one, you know it’s not just uncomfortable; it’s downright painful. It’s all about bacteria getting into your urinary tract and the symptoms aren’t subtle. Think of burning pain when you pee, a constant need to go (even when you just went), and sometimes, an ache in your lower belly. Not fun.

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Now, sepsis is like the boss’s level of infection. It’s when an infection, even something as “simple” as a UTI, goes rogue and spreads throughout your body. Sepsis is no joke—it’s a life-threatening condition that can turn deadly if not treated quickly. It’s basically your body going into overdrive to fight the infection, but in doing so, it can cause even more damage.

Sepsis is a life-threatening situation, that leads to organ dysfunction, Most patients with sepsis end up in the ICU.

Early diagnosis is a problem, because we are still dependent on culture, as it takes up to 3 days. We need fast methods to detect early sources of infection and AMR. 

But being such a severe problem, still we do not have any fast solution till 2022, to treat sepsis in time, which leads to one organ failure towards several organ failures if not treated in time. Doctors prescribe symptom-based broad-spectrum antibiotics, it may work or not, but they have to wait for culture for 3 days. Which causes AMR (antimicrobial resistance due to high dose antibiotics consumption). You may have a patient who was on ventilation on day 1 and within 2-3 days, had other organ failures, like dialysis or hypertension – they all are due to AMR, or the wrong antibiotic on day 1 without test-based treatment.

Now we can change this practice using  PRATHAMA SENSE Genosensor, which is a gene-based detection method, that will give you results of UTI, Sepsis, and antimicrobial resistance in just 90 minutes, which will help doctors in prescribing the right antibiotics at the right time and TREATMENT of sepsis, UTI, pneumonia and so on within 90 minutes.  There will high chance now, i.e. patients will not enter into one organ to the other organ failure as they received test-based antibiotics. This situation, will not only improve patient health but also reduce financial burden, as high-grade antibiotics are very costly (10k to 1 lakh for 5 days for antibiotics course only, rest expense is not added).

The Scary Thing About Antimicrobial Resistance

Here’s where things get even scarier: antimicrobial resistance, or AMR. We’ve all heard about bacteria getting smarter, right? Well, that’s exactly what’s happening. They’re evolving to the point where some antibiotics don’t work anymore. Imagine being sick, taking antibiotics, and… nothing happens. That’s the nightmare scenario with AMR.

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What’s crazy is that this isn’t some far-off problem; it’s happening now. The more we use antibiotics, especially when they’re not needed, the more we’re training bacteria to outsmart us. This makes it harder to treat even basic infections and turns serious ones like sepsis into a race against time.

How We Usually Treat These Infections

Typically, when you come down with something like a UTI, sepsis or pneumonia, your doctor will put you on antibiotics based on what they *think* will work. Sometimes they’ll run tests, but those can take forever—or at least it feels that way when you’re sick and waiting for answers. In the meantime, you’re either stuck with a treatment that might not work or just waiting it out, which is the last thing you want to do if you’re dealing with something as serious as sepsis.

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And if the bacteria causing your infection are resistant to the antibiotics you’re given? Well, it’s like taking a sugar pill—useless.

The Tech That’s Changing Everything: RAMJA Genosensor

Here’s the cool part—there’s this new technology called the RAMJA Genosensor that’s shaking things up in the best possible way. It’s a device that can identify the bacteria causing your infection and check if they’re resistant to any antibiotics, all in just 90 minutes. Yup, you heard me right—90 minutes!

RAMJA Genosensor

Here’s how it works: They take a sample from you (blood, urine or any biological fluid), and the Genosensor gets to work. It hunts down the specific bacteria causing your infection and figures out if they’ve developed any resistance to antibiotics. So, instead of waiting days for test results and playing the guessing game with meds, you get the right answer fast.

RAMJA Genosensor

Why RAMJA Genosensor is a Big Deal

Let me tell you why I’m so excited about this:

1. Speedy Answers: Getting results in 90 minutes is a game-changer. It can help in the treatment of sepsis, UTI, pneumonia, etc. The faster you know what’s going on, the faster you can get on the right treatment and start feeling better.

2. Tailored Treatment: Since the Genosensor checks for resistance, you’re not just getting any antibiotic—you’re getting one that’ll actually work for your specific infection. No more wasting time on meds that don’t do the job.

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3. Fighting The AMR Battle: By using the right antibiotics from the get-go, we’re helping to prevent bacteria from becoming even more resistant. It’s a win for you and a win in the larger fight against AMR.

4. Peace Of Mind: There’s something super reassuring about knowing you’re getting the best possible treatment. With RAMJA Genosensor, you’re not left guessing—you’ve got solid, reliable info guiding your care.

What This Means For You And Me

Honestly, learning about this has totally changed how I think about infections and treatments. I used to just go along with whatever the doctor prescribed, but now I’m all about making sure we’re using the best tools out there my infection detection. And RAMJA Genosensor? It’s like having a secret weapon in the fight against these bugs.

RAMJA Genosensor

So, the next time you’re feeling under the UTI, sepsis, pneumonia, typhoid, or any other infection, know that there’s some seriously smart tech out there that’s got your back. Here’s to staying healthy and keeping those pesky bacteria in check!

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